As seen above, one molecule of glucose oxidized by aerobic respiration in prokaryotes yields the following:. Learning Objectives The theoretical maximum yield of ATP for the oxidation of one molecule of glucose during aerobic respiration is In terms of substrate-level phosphorylation, oxidative phosphorylation, and the component pathways involved, briefly explain how this number is obtained.
Oxidative phosphorylation and the electron transport chain. Practice: Oxidative phosphorylation and the ETC. Calculating ATP produced in cellular respiration. Next lesson. Current timeTotal duration Google Classroom Facebook Twitter. Video transcript - [Instructor] Alright, so, if we were gonna go on the ambitious task of tallying up how much ATP was produced in one cycle of cellular respiration or, just to be super clear here, I mean how much ATP was produced per the oxidation or breakdown of one molecule of glucose in cellular respiration?
We might start off by just getting ourselves organized and reminding ourselves that there are two kind of main ways that we produce ATP in cellular respiration so, the first minor contribution comes from something called substrate level phosphorylation. And remember that this is exactly what it sounds like, we have a substrate, or a molecule, I'm just gonna say R. And remember that in the context of cellular respiration, this is usually, we think of this as a kind of metabolite, an intermediate metabolite of glucose, so somewhere along glucose is oxidation.
We get a metabolite and we activate this metabolite with a phosphate group. And from this phosphate group, we can actually donate it directly to ADP to produce ATP, and of course our molecule also gets modified in the process, usually gaining a hydroxy group, but the details aren't entirely important except to realize that this phosphorylation is occurring at the level of a substrate.
This is in contrast, of course, to oxidative phosphorylation, which is where we get the bulk of our ATP. And this oxidative refers to the fact that this process requires oxygen and in fact, the importance of oxygen here is that this oxygen is reduced by electron carrier molecules and something called the electron transport chain so, remember that we have a electron carrier molecules called NADH and FADH two that are produced at various stages of cellular respiration, glycolysis, the oxidation of pyruvate, the Krebs Cycle, and it's basically storing up all of that energy from the glucose molecule and it's gonna donate it into the electron transport chain, and of course the final electron acceptor is oxygen, which is then reduced to water.
But the important here is that this flow of electrons is able to power something, essentially fuel something called ATP synthase which is an enzyme that is in the mitochondrial membrane that produces the bulk of our ATP. Now, the next point I want to make here is that it's actually been possible for us to calculate the exact number of ATP produced in substrate level phosphorylation and we've also nailed down the amount of NADH and FADH two molecules that are produced in this process as well.
But for a quite a while, it was difficult to nail down the exact number of ATP molecules that were produced in oxidative phosphorylation. Hydrogen carriers produce different amounts of ATP depending on where they donate electrons to the transport chain.
Summary of ATP Production. Overview of Aerobic Respiration. Brent Cornell. Cell Introduction 2. Cell Structure 3. Membrane Structure 4. Membrane Transport 5. Origin of Cells 6. Cell Division 2: Molecular Biology 1. Metabolic Molecules 2.
Water 3. Protein 5. Enzymes 6. Cell Respiration 9. Photosynthesis 3: Genetics 1. Genes 2. Chromosomes 3. Meiosis 4. Inheritance 5.
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